Sophie Dupuis-Girod Selected Research

Hereditary Hemorrhagic Telangiectasia

1/2021	An international, multicenter study of intravenous bevacizumab for bleeding in hereditary hemorrhagic telangiectasia: the InHIBIT-Bleed study.
4/2020	Efficacy and Safety of a 0.1% Tacrolimus Nasal Ointment as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia: A Double-Blind, Randomized, Placebo-Controlled, Multicenter Trial.
1/2020	Intravenous Bevacizumab in Hereditary Hemorrhagic Telangiectasia: A Role That Is Still to Be Defined.
1/2020	Sequence variations of ACVRL1 play a critical role in hepatic vascular malformations in hereditary hemorrhagic telangiectasia.
1/2019	Efficacy of TIMOLOL nasal spray as a treatment for epistaxis in hereditary hemorrhagic telangiectasia. A double-blind, randomized, placebo-controlled trial.
1/2019	Recurrence of Hereditary Hemorrhagic Telangiectasia After Liver Transplantation: Clinical Implications and Physiopathological Insights.
1/2019	Prevention of serious infections in hereditary hemorrhagic telangiectasia: roles for prophylactic antibiotics, the pulmonary capillaries-but not vaccination.
1/2019	Safety of thalidomide and bevacizumab in patients with hereditary hemorrhagic telangiectasia.
1/2017	Intra-venous bevacizumab in hereditary hemorrhagic telangiectasia (HHT): A retrospective study of 46 patients.
1/2017	Response to Bevacizumab for the treatment of Rendu-Osler disease-A note of caution.

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Sophie Dupuis-Girod Research Topics

Disease

19	Hereditary Hemorrhagic Telangiectasia 01/2021 - 03/2010
11	Epistaxis (Nosebleed) 01/2021 - 04/2010
3	Hemorrhage 01/2021 - 04/2010
3	Marfan Syndrome (Marfan's Syndrome) 04/2020 - 08/2015
3	Telangiectasis (Telangiectasia) 01/2020 - 04/2010
3	Infections 01/2019 - 01/2005
3	Vascular Malformations 04/2013 - 03/2010
3	Ectodermal Dysplasia (Aplasia Cutis Congenita) 07/2006 - 10/2003
2	Anemia 01/2021 - 04/2010
2	Proteinuria 01/2021 - 01/2019
2	Inborn Genetic Diseases (Disease, Hereditary) 02/2012 - 09/2009
2	hypohidrotic Ectodermal dysplasia with immune deficiency 10/2003 - 06/2002
1	Hypertension (High Blood Pressure) 01/2021
1	Fatigue 01/2021
1	Neurodevelopmental Disorders 01/2020
1	Aortic Valve Insufficiency (Aortic Regurgitation) 01/2020
1	Dizziness (Lightheadedness) 01/2019
1	Headache (Headaches) 01/2019
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2019
1	Arthralgia (Joint Pain) 01/2019
1	Iron Deficiencies 01/2018
1	Aortic Dissection 12/2016
1	Aortic Diseases 12/2016
1	Hypertelorism 12/2016
1	Cicatrix (Scar) 12/2016
1	Sudden Death 08/2015
1	Neoplasms (Cancer) 08/2015
1	Thoracic Aortic Aneurysm 12/2014
1	Vascular Diseases (Vascular Disease) 05/2014
1	Edema (Dropsy) 04/2013
1	Mitral Valve Insufficiency (Mitral Regurgitation) 04/2013
1	Dyspnea (Shortness of Breath) 04/2013
1	Atrial Fibrillation 04/2013
1	Brain Abscess (Abscess, Brain) 04/2012
1	High Cardiac Output 03/2012
1	Heart Failure 03/2012
1	Thrombocytosis (Thrombocythemia) 02/2005
1	Erythropoietic Porphyria (Congenital Erythropoietic Porphyria) 02/2005
1	Essential Thrombocythemia 02/2005
1	Eosinophilia 02/2005
1	Adenoviridae Infections (Adenovirus Infections) 01/2005
1	Bacterial Infections (Bacterial Infection) 10/2003
1	Thrombocytopenia (Thrombopenia) 05/2003
1	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 05/2003
1	X-Linked Combined Immunodeficiency Diseases (X Linked Severe Combined Immunodeficiency) 04/2002

Drug/Important Bio-Agent (IBA)

10	Bevacizumab (Avastin)FDA Link 01/2021 - 02/2012
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 04/2013
4	NF-kappa B (NF-kB)IBA 07/2006 - 06/2002
3	Nasal SpraysIBA 01/2019 - 05/2014
2	Hemoglobins (Hemoglobin)IBA 01/2021 - 04/2010
2	Monoclonal AntibodiesIBA 01/2017 - 01/2016
2	EndoglinIBA 02/2015 - 05/2014
2	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 05/2014 - 01/2012
2	Biological ProductsIBA 04/2012 - 02/2005
2	Cidofovir (Vistide)FDA Link 01/2009 - 01/2005
2	I-kappa B KinaseIBA 07/2006 - 10/2003
2	NF-KappaB Inhibitor alphaIBA 07/2006 - 10/2003
1	IronIBA 01/2021
1	Immunosuppressive Agents (Immunosuppressants)IBA 04/2020
1	Ointments (Pastes)IBA 04/2020
1	Tacrolimus (Prograf)FDA LinkGeneric 04/2020
1	Amino Acids FDA Link 04/2020
1	Proteins (Proteins, Gene)FDA Link 01/2020
1	Transcription Factors (Transcription Factor)IBA 01/2020
1	Thalidomide (Thalomid)FDA Link 01/2019
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2019
1	Pharmaceutical PreparationsIBA 01/2019
1	Timolol (Blocadren)FDA LinkGeneric 01/2019
1	Fibrillin-1IBA 01/2017
1	Transforming Growth Factor-beta Type II ReceptorIBA 12/2016
1	Transforming Growth Factor-beta Type I ReceptorIBA 12/2016
1	Losartan (Cozaar)FDA LinkGeneric 08/2015
1	Activin Receptors (Activin Receptor)IBA 02/2015
1	1,3,4,6- tetra- O- acetyl- 2- azido- 2- deoxyglucopyranose (TAAD)IBA 12/2014
1	Brain Natriuretic Peptide (Natrecor)FDA Link 04/2013
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2012
1	Capsules (Microcapsules)IBA 04/2010
1	Transforming Growth Factor beta (TGF-beta)IBA 09/2009
1	Antiviral Agents (Antivirals)IBA 01/2005
1	Ribavirin (Virazole)FDA LinkGeneric 01/2005
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2003
1	Serine (L-Serine)FDA Link 10/2003
1	LigandsIBA 10/2003
1	Immunoglobulin M (IgM)IBA 05/2003
1	Biological FactorsIBA 05/2003
1	Codon (Codons)IBA 06/2002

Therapy/Procedure

4	Therapeutics 01/2020 - 01/2005
4	Liver Transplantation 01/2019 - 03/2010
4	Stem Cell Transplantation 07/2006 - 04/2002
2	Aftercare (After-Treatment) 01/2021 - 04/2020
1	Nasal Surgical Procedures 01/2019
1	Operative Surgical Procedures 01/2018
1	Antibiotic Prophylaxis 01/2018
1	Transplantation 07/2006
1	Hematopoietic Stem Cell Transplantation 07/2006
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 02/2005
1	Splenectomy 05/2003